Friday, April 29, 2016
The Coffee³ Advantage Equation 3 x 250mL Coffee Day 2x4 Weeks ? 1kg Body Fat Satiety ? Ghrelin ? 5HT ? Cancer Protective 16 Reduction in DNA Breaks Health³
Here it is: Scientific evidence caffeine is the among the healthiest addictions known to man. |
If you take a look at the study design, you will see that we are dealing with a five-months study with three four-week washout periods, a crossover and two different types of coffee that was tested on two groups.
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Figure 1: Graphical overview of the study design (Bakuradze. 2014); adherence was controlled by urine essays. |
Regardless of the type of coffee and/or study period, subjects were instructed to prepare their three coffees à day with two of the 7.5 g coffee pods and to consume their freshly brewed coffee in 250ml portions spread relatively evenly across the day ... which yielded the already mentioned benefits (see Figure 1):
Figure 2: Rel. changes in body fat, fat free mass (incl. bone), serotonine and active grehlin levels (hunger) after 4 weeks on the different coffee brands; data from A |
Ah, and before I forget to tell you. In contrast to what the title of the paper, i.e. "Four weeks coffee consumption affects energy intake, satiety regulation, body fat, and protects DNA integrity" would suggest, there was no significant reduction in energy intake that could explain the fat loss, let alone body-recompositioning effects you can see in Figure 2 (left).
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In essence, this is yet possible, but very unlikely. An attenuation of brain serotonin has after all only been observed in the short term (Haleem. 1995). To assume that the benefits we are seeing in the study at hand are just the results of the compensation of a previous crash of serotonin and increase in grehlin and appetite that occurred in response to caffeine withdrawal does therefore appear to be another far-fetched caffeine hater hypothesis ;-)
- Haleem, Darakhshan J., et al. "24h withdrawal following repeated administration of caffeine attenuates brain serotonin but not tryptophan in rat brain: Implications for caffeine-induced depression." Life sciences 57.19 (1995): PL285-PL292.